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Human bio 2021


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Erin Harries


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[Front]


cell theory
[Back]


all organisms are made of cells, which are the basic unit of life and arise from pre-existing cells

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Cell theory
All organisms are made of cells, which are the basic unit of life and arise from pre-existing cells
Cell membrane
Separates cell contents from outside the cell encloses cell contents and controls what enters and leaves is
Cytoplasm
Jelly like, watery material fills space between nucleus and cell membrane made from cytosol and organelles
Cytosol
The liquid part of the cytoplasm where most metabolic reactions occur controls osmotic pressure inside the cell dissolved salts and carbohydrates
Nucleus
Largest organelle in the cell oval/spherical
Nuclear pores
Allow large molecules, such as messenger rna to enter and leave the nucleus
Nuclear membrane
Separates nucleus from cytoplasm double membrane
Dna
Inside nucleus contains information that determines type of protein cell can make controls the structure and function of the cell nucleolus also plays a part in manufacturing proteins
Ribosomes
Small, spherical where amino acids are joined to make proteins can be free in cytoplasm or connected to other organelles
Endoplasmic reticulum
Membranes that form channels in cytoplasm used for storage, support, synthesis and transport in the cell rough has ribosomes, smooth doesn't
Golgi body
Flattened, stacked membranes, usually near the nucleus modifies proteins and packages them for secretion proteins produced at ribosomes pass through ER to the golgi body at the edges of the membranes, small sacs of proteins are formed, surrounded by a membrane called vesicles
Lysomes
Formed from golgi body, bound by membrane digestive enzymes break down large molecules vesicles that enter the cell and worn out organelles join with lysomes to be broken down
Mitochondria
Double membrane, outside surrounds mitochondrion inner membrane (cristae) folds inside where cellular respiration and some chemical reactions occur
Fcilia and flagella
Fine projections that can beat back and forth to move substances/molecules tiny 'hairs' are cilia, longer ones are flagella cilia in trachea flagella are on sperm
Cytoskeleton
Framework of protein fibers that shape cell and assist movement
Intwo types of cytoskeleton
Microtubules-hollow rods, hold/move organelles microfilaments-move materials around cell/move cell
Inclusions
Chemical substances not part of cell structure, found in cytoplasm eg. haemoglobin and pigment melanin
Fluid mosaic model explains what
Structure and function of the membrane (constantly moving and made up of many different molecules
Cell membrane composed of...
Phospholipids, form a bilayer
Structure of phospholipids
Hydrophobic head 2 hydrophilic tails
Properties of phospholipid bilayer
Held together by weak hydrophobic interactions in tails phospholipids and other materials move within bilayer fluid, can break and reseperate
Composition of the bilayer
Cholesterol and protein molecules embedded important for function integrity and stability of membrane
Functions of the cell membrane
Physical barrier-separates cell from surroundings regulate passage of materials-controls movement of materials entering and leaving sensitive to changes-first thing affected by changes outside cell supports cell-internal part of cell membrane is attached to cytoskeleton-connections between other cells membrane, providing whole tissue support
Simple diffusion
Molecules diffuse through the membrane along concentration gradient co2, o2, fatty substances, steroids, alcohol
Osmosis
Where solvent moves across a semi permeable membrane to where a solute is in higher quantity simple diffusion
Protein channels
Water soluble molecules diffuse through channel large molecules don't fit facilitated diffusion
Carrier meditated transport
One end open at a time specific to one particle become saturated, proteins can only process a certain amount in a certain time regulated by hormones
Facilitated diffusion
Along concentration gradient molecule attaches to a binding site on a specific protein, protein then changes shape to allow molecule to be released on the other side of the membrane carrier meditated transport
Active transport
Requires atp against concentration gradient similar to facilitated diffusion
Vesicular transport
Where droplet or solid enters or leaves cell
Endocytosis
Coming into the cell, membrane folds over and then pinches off pinocytosis-liquid phagocytosis-solid
Exocytosis
Out of the cell, fuses with membrane
Cell inputs
Oxygen, nutrients(lipids, amino acids, glucose), minerals, ions, vitamins, water
Cell outputs
Co2, toxic substances, proteins (hormones...
Epithelial tissue
Covering or lining tissue closely joined cells thin, flat, column, cube, etc. depending of the tissue line inside and/or outside of the heart, kidney, lungs
Epithelial tissue (epithelium)
Covering or lining tissue closely joined cells thin, flat, column, cube, etc. depending on tissue line inside and/or outside of heart kidney lungs
Connective tissue
Provides support, holds body parts together separated by large amounts of material not made from cells (matrix)
Connective tissue eg
Bone, cartilage, tendon, ligament, fat storage, blood
Types of muscular tissue
Skeletal, smooth, cardiac
Skeletal muscle tissue
Muscle attached to bones voluntary muscle stirated muscle
Smooth muscle tissue
So stirations involuntary stomach, intestines, iris, uterus
Cardiac muscle
Makes up most of the heart, pumps blood involuntary stirations
Nervous tissue
Neurons have long projections from the body of the cell when stimulated, messages are carried along projections from one part of the body to another nervous tissue found in brain, spinal cord, nerves
Metabolism def
All the chemical reactions that take place in the cell
Catabolic metabolism and example
Broken down to smaller molecules releases atp eg. digestion
Anabolic reaction def and eg
Built up to larger molecules requires atp eg. protein synthesis
Define nutrients
Any substance in food that is used for growth, repair or maintaining the body.
Six main groups of nutrients
Water carbohydrates lipids proteins minerals vitamins
Organic compounds
Have a carbon chain have a number of hydrogen atoms, can also include oxygen, nitrogen, sulfur, dna and rna
Carbohydrates
Main source of energy for the cell monosaccharides (mostly glucose) release energy poly/disaccharides broken down before entering cell eg. starch made of carbon, hydrogen, oxygen
Organic compounds eg
Carbohydrates, proteins, lipids
Lipids
Fats, oil and another important energy source broken down to fatty acids and glycerol contains one molecule of glycerol and 1-3 fatty acids glycerol breaks down similar to glucose
Proteins
Made of amino acids 100 or more amino acids in a single protein have characteristic shapes
Essential amino acids
Ones the body cant produce, so it must consume
Amino acids
Contain an amino group and a carboxylic acid group 20 different types found in proteins, each differing on structure of side chain. 2 bond to form a peptide bond shorter ones are called dipeptides and polypeptides
Inorganic compounds
Not based on carbon chain some reactions occur in water, some water takes part in the reaction
Inorganic compounds egs
Minerals vitamins
Minerals
May be part of enzymes, function as cofactors for enzymes or be a part of substances such as atp
Vitamins
Coenzymes for many chemical reactions of metabolism.
Enzymes
Biological catalysts used to speed up chemical reactions react with one specific molecule
Lock and key model
Enzyme is always complementary to shape of substrate, therefore the two will fit exactly to form the enzyme substrate complex
Induced fit model
When enzyme and substrate join, weak bonds are formed that change enzyme shape to create complementary shapes
Factors affecting enzyme activity
Shape and availability of active site concentration of enzyme/substrate temperature pH levels
Cofactors?
Used by enzymes to change shape of active site, so that enzyme can combine with substrate. eg. certain ions or non-proteins, minerals
Cellular respiration def
The process by which organic molecules are broken down in the cells to release energy for cellular activity
Cellular respiration can release energy from...
Glucose, amino acids, fatty acids, glycerol