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Human Biology-Response to Infection

--Following 'Human Perspectives' text book , 8th edition, star units 3 & 4 + lecture notes (Chapter 7 (p 155-197) & chapter 8 (p 199-230)) --Academic Associates Study Guide --Crewman Exam Questions CREATED 2024- BY STUDENT


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Human Biology-Response to Infection


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what is host specific mean (virus)
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refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.

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What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
What are the qualities of COMMUNICABLE DISEASE
-(infectious/transmissible) -Caused by foreign organisms invading the body and multiplying -contagious -passed by contact or vector (intermediate host, eg mosquito)* -pathogens *
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
What are the qualities/qualifications of BACTERIA
-Most are non pathogenic -eg. decomposition, human digestion -Microscopic single celled organisms -Rapid multiplication can kill cells -Can secrete toxins -Classified by cell shape -can contain both DNA and RNA
Pathogens?
Disease causing organisms most common= bacteria and virus can include fungi and parasites
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
Cocci
Spherical cells - bacteria
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
Bacilli
Cells with flagella - bacteria
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
Spirilla
Twisted cells- bacteria
Vibrio
Curved rods, comma like cells- Bacteria
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
What is the role of vectors and common vector borne diseases
Vectors are frequently arthropods, such as mosquitoes, ticks, flies, fleas and lice. carry pathogens that can multiply within their bodies and be delivered to new hosts, usually by biting. -Malaria (mosquitos) -yellow fever -Lyme disease (ticks)
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
Label virus and describe structure
Glycoprotein spike -petruding protein envelope -on surface RNA or DNA internal nucleocapsid -nucleic acid + protective capital internal membrane protein-external.
Pathogenic organisms & examples
Bacteria- ghoneria, clamidia, syphillus, phnumonia Animal Parasites- lice, tape worms, malaria virus - covid, ross river, fungi -
What are the qualities/qualifications of Viruses
Contain DNA or RNA surrounded by capsid(protein coat) ^ Induces host to manufacture more virus particles (CANNOT REPRODUCE ALONE) most insert genetic material or enter cell through endocytosis
Bacteriophanges
Virus using bacteria as host
Cell lycing
The breakage of cell membrane due to over replication of virus within
Transmission modes of pathogens
Contact body fluids airborne transmission ingestion droplets vectors
Non specific defences overview
Innate immune system works against ALL pathogens first line of defence
Types of non specific defence -EXTERNAL
Skin -oil sebum barrier, sweat Mucous membranes - line cavities, mucous inhibit entry lysosomes-enzyme that kill bacteria, eyes Acids eg stomach, vag, sweat hair + cilia cerumen -wax flushing action urine, anal
Specific defences overview
Adaptive/ acquired immune system directed at particular pathogens ie antibodies formed after illness
Phagocytes +two examples
Cells that can engulf and digest(destroy) micro organisms/ eliminate pathogens eg. leucocytes (white bc) & microphages
Inflammatory response purpose
Reduce -pathogen spread, destroy them, prevent entry Remove - damaged tissue/ cell debris Repair- damaged tissues
Signs of inflammatory response
Red, Heat, Swelling, Pain
Endocytosis
Endocytosis is a general term describing a process by which cells absorb external material by engulfing it with the cell membrane - occurs with virus such as influenza
Lysogenic cycle (HIV multiplication method)
The virus bind to a cells receptors inserts its DNA into the cell, allowing the virus RNA to be copied and passed on along with the cell's own DNA producing new viral RNA, to be release to infect other cells - eg HIV multiplication using lymphocytes
Lytic cycle ( Influenza multiplication method)
The virus introduces its genome into a host cell and initiates replication by hijacking the host's cellular machinery to make new copies of the virus. continue until cell bursts (cellular lysis)
Cell lysis
Breakage of cellular membrane due to rapid viral multiplication overfilling cytoplasm + increasing pressure. killing of cells/ disruption to regular activity causes symptoms of illness
Binary fission
Reproduction method where organisms double in material then split in two - used by bacteria
What is plan C
How antibodies work precipitation lysis agglutinin neutralisation coat
Coat
Tbc
What is host specific mean (virus)
Refers to the specific cell viruses must occupy and use to replicate due to the specific viral receptors on the host cell surface. required for the virus to attach to the cell.
Describe phagocytosis. what white blood cell is actively engaged in it
The ingestion of bacteria, dead cell materials or particles by cells it is the major function of macrophages the pathogen interacts with phagocyte receptors phagocyte envelops pathogen and activates lysozyme pathogen is digested and broken down into proteins complex formed including pathogen DNA to form a major histocompatability complex (MHC) -antigen (adaptive immunity