Peripheral Circulation
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🇬🇧 | 🇬🇧 |
What are the different walls of arteries and veins | Tunica intima → next to the lumen Tunica media → intermediate Tunica adventitia → outer layer |
What are the 3 types of arteries | Elastic conducting arteries → widest Muscular distributing arteries → intermediate diameter Arterioles → narrowest |
What happens when blood flow is cut off to the limb and when it returns | When there is no blood flow, metabolites accumulate, so arterioles dilate maximally When flow is returned, resistance is very low so flow is very high but high flow washes away the metabolites and so smooth muscle constricts again |
What are the 3 types of capillaries | Continous Capallaries --> most common type, nervous, muscle etc. locations Fenestrated capillaries --> gut, endocrine glands and renal glomerulus Discontinous --> In liver, spleen and bone marrow, generally wider and slower blood flow |
What are some examples of vasodilator molecules and their mode of action | H+ K+ Adenosine These act as relax vascular smooth muscle --> vasodilation |
An increase in metabolism leads to what in the bloodstream | If metabolism increases more metabolites are produced So concentration increases, vasodilation occurs Vasodilation leads to an increase in flow Increased flow washes away the metabolites and more metabolism leads to more blood flow |
What Vasomotor tone | Tonic contraction of smooth muscle known as vasomotor tone Increases known as vasoconstriction |
Factors affecting contraction of vascular smooth muscle : | Vasomotor tone mostly produced by the sympathetic branch of the autonomic nervous system This tone is antagonised by vasodilator factors The actual resistance determined by balance between the two |