Renal Pathologies
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Renal Pathologies - Details
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Clinical manifestations: proteinuria, hypoalbuminemia, general edema, hypercholesterolemia and lipidura | Nephrotic syndrome |
Most common cause of nephrotic syndrome in children's from 2-6 years of age. | Minimal change disease |
Biopsy: Light microscopy: No abnormalities Immunofluorescence: Negative Electron microscopy: Foot process enfacement | Minimal Change disease |
Most common Renal disease in adults. | Focal segmental glomerulosclerosis |
Clinical pathophysiology syndrome: -Podocyte injury and depletion -Glomerular segmental scarring (sclerosis) | Focal segmental glomerulosclerosis |
20-30% is in Caucasian adults, during 4-5 decades of life most common in men. Light microscopy: capillary walls appear thickened Biopsy: Immunofluorescence: IgG & C3 | Membranous nephropathy |
Reduction of GFR, Non - nephrotic proteinuria, edema, hypertension, RBC cast, Azotemia, oliguria and hematuria. | Nephritic syndrome |
Appears after 1-4 weeks after Streptococcal infection (A-B hemolytic Strepotococci). Most common in children's of 6-10 years | Poststreptococcal glomerulonephritis |
Malaise, fever, oliguria and hematuria (weeks later after trot infection) | Post strep glomerulonephritis symptoms |
Rapid progressive loss of renal function. Biopsy: Crescentic glomerulonephritis | Rapidly progressive glomerulonephritis |
10% of the people are born with malformations of the urinary system, it can be in early development of later( hydronephrosis and nephron loss can occur) | Congenital Urinary Tract obstruction |
Solitary kidney enlarges as a compensatory hypertrophy and it can develop some glomerular sclerosis. | Agenesis of the kidney |
Kidney lies above the pelvic brim or within the pelvis. | Ectopic kidney |
Fusion of the upper or lower pole of the kidney and it continues across the midline anterior to the great vessels | Horseshoe kidney |
Detects hydronephrosis and hydroureter | Ultrasound |
Small tumors (<.5cm) Appears pale yellow, discrete well circumscribed nodules | Renal Papillary ademona |