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level: Level 1

Questions and Answers List

Question	Answer
word root meaning inflammation	-itis
four cardinal signs of inflammation	heat, redness, swelling & pain
enlargement of the diameter of a blood vessel	vasodilation
increases “leakiness” of a blood vessel	vasopermeability
substance that initiates pain signals from nerve endings	bradykinin
a foreign substance that initiates an immune response	antigen
antigen from unlike species that elicit cross reactive antibodies	heterophile antigen
self-antigens usually hidden from the immune system	sequestered antigen
immunologically privileged sites	testes, womb, cornea, CNS
antigens that non-specifically activate a lot of T cells	superantigens
a transplant from a different species	xenograft
a transplant from one part of your body to another	autograft
a transplant from a genetically dissimilar person	allograft
a transplant from an identical twin (genetically identical)	isograft (syngeneic)
molecules on cells that cause transplant rejection	class I MHC (HLA) molecules
matches HLA molecules between donors & recipients	tissue typing
most be harvested from a living donor	organs
may be harvested from a deceased donor	tissues
self antigens	autologous antigens
antigens from a genetically identical donor	syngeneic (isogeneic) antigens
antigens from a genetically different person	allogeneic antigens
antigens from a different species	xenogeneic antigens
when the immune system attacks a transplant	transplant rejection
a syndrome which occurs in people with AIRE mutations	APECED