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level: DETERMINATION OF THE PHYSICAL PROPERTIES OF MOLECULES

Questions and Answers List

Question	Answer
Basic unit of matter; consists of a dense central nucleus; surrounded by a cloud of negatively charged electrons.	• Atom
Atoms are Neutral, that means	• (same numbers of positive and negative charges)
Adding or taking away negative charges	• Charged atoms
It is a charged atom	• Ion
Atomic mass refers to	Protons + Neutrons
Atomic number refers to	Protons + Electrons
Protons and Electrons have the same __	Value
• They are variants of a particular chemical element	Isotopes
• All isotopes of a given element have the same number of protons in each atom but they differ in __	Neutron Number
WHAT ARE THE PROPERTIES OF MOLECULES?	• Additive property • Constitutive property
• The sum of the corresponding properties of the atoms that constitute the molecule • Ex. Molecular mass = atomic masses of the constituent atoms	Additive property
• Depends upon the arrangement of the atoms within the molecule • Ex. Optical activity of a molecule, electrical property	Constitutive property
What are their relevance to Pharmacy (PROPERTIES OF MOLECULES)?	• We can describe the spatial arrangement of atoms in drug molecules • Provide evidence for the relative chemical or physical behaviour of a molecule • Suggest methods for qualitative and quantitative analysis of a particular pharmaceutical agent • (This will also guide the FDA in ensuring human safety and drug efficacy)