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Index
»
DDS LEC FINALS
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Chapter-13.-Solutions.pptx
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SYRUPS METHOD OF PREPARATION
level: SYRUPS METHOD OF PREPARATION
Questions and Answers List
level questions: SYRUPS METHOD OF PREPARATION
Question
Answer
Syrups are prepared by this method when it is desired to prepare the syrup as quickly as possible, when the syrup’s components are not damaged or volatilized by heat.
Ⅰ. Solution With the Aid of Heat
1 Because of the prospect of decomposition by heat, syrups cannot be sterilized by __
1 Autoclaving
The use of this in the preparation of a syrup can enhance its permanency
boiled purified water
the addition of this, when permitted, CAN PROTECT IT DURING ITS SHELF LIFE
preservative agents
Storage of all syrups
a tight container
To avoid heat-induced inversion of sucrose, a syrup may be prepared with this more time consuming than use of heat, but the product has MAXIMUM STABILITY Huge glass-lined or stainless steel tanks with mechanical stirrers or agitators are employed in large-scale preparation of syrups. On a small scale, sucrose and other formulative agents may be dissolved in purified water and thorough agitated of the mixture.
Ⅱ. Solution by Agitation Without the Aid of Heat
Occasionally a medicated liquid, such as a tincture or fluidextract, is employed as the source of medication in the preparation of a syrup. Many such tinctures and fluidextracts contain alcohol-soluble constituents and are prepared with alcoholic or hydroalcoholic vehicles. If the alcohol-soluble components are desired medicinal agents, some means of rendering them water soluble are employed If the tincture or fluidextract is miscible with aqueous preparations, it may be added directly to simple syrup or to a flavored syrup.
Ⅲ. Addition of Sucrose to a Medicated Liquid or to a Flavored Liquid
In the this method, either sucrose may be percolated to prepare the syrup, or the source of the medicinal component may be percolated to form an extractive to which sucrose or syrup may be added. This latter method really is two separate procedures: first the preparation of the extractive of the drug and then the preparation of the syrup.
Ⅳ. Percolation
Example of syrup prepared by percolation what is the dose of this syrup? This amount of syrup is commonly used in the management of poisoning in children when the evacuation of the stomach contents is desirable.
Ipecac Syrup, usual dose: 15 mL Ipecac syrup also has some application as a nauseant expectorant, in doses smaller than the emetic dose.
Preparation of Ipecac Syrup
1 Add glycerin and syrup to an extractive of powdered ipecac obtained by percolation 2 Alkaloids are extracted from the powdered ipecac by percolation