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level: level 8

Questions and Answers List

level questions: level 8

Question	Answer
- aqueous suspensions of insoluble, inorganic drugs - differ from gels mainly in that the suspended particles are larger. - are thick and viscous, so need of a suspending agent. - gel mass consisting of floccules of small distinct particles as a two-phased system.	MAGMAS and MILK
Preparation of magmas and milk	1 Hydration 2 Chemical Reaction
- pressured dosage forms containing one or more active ingredients which upon actuation emit a fine dispersion of liquid and/or solid materials in gaseous medium - a colloidal dispersion of a gas in liquid	AEROSOLS
commonly used referring to the aerosol container or completed product Pressure is applied to the aerosol system through the use of one or more liquefied or gaseous propellants.	Pressurized package
Aerosols used to provide an airborne mist Example: room disinfectants, room deodorizers, and space insecticides.	Space sprays
Aerosols intended to carry the active ingredient to a surface Examples: dermatologic aerosols, pharmaceutical aerosols, as personal deodorant sprays, cosmetic hair lacquers and sprays, perfumes and cologne sprays, shaving lathers, toothpaste, surface pesticide sprays, paint sprays and others	Surface sprays or surface coatings
Advantages of the Aerosol Dosage Forms	Easily withdrawn Hermetic character Applied in a uniform, thin layer Emitted product may be controlled “clean” process (NO NEED TO WASH)
The aerosol principle	1. The product concentrate 2. The propellant
is the active ingredient of the aerosol combined with the required adjuncts, such as antioxidants, surface-active agents, and solvents, to prepare a stable and efficacious product.	The product concentrate
when the propellant is __, it frequently serves the dual role of propellant and solvent or vehicle for the product concentrate	a liquefied gas or a mixture of liquefied gases
Examples of Propellants	1. Carbon dioxide 2. Nitrogen 3. Nitrous oxide 4. Fluorinated Hydrocarbons
phased out as propellant of aerosol	CFC (chloroflurocarbon)
The pressure of an aerosol is critical to its performance. It can be controlled by	1. The type and amount of propellant 2. The nature and amount of material comprising the product concentrate
usually operate at pressures between 30 to 40 psig ( pounds per square inch gauge )at 70F and may contain as much as 85% propellant	Space aerosols
commonly contain 30 to 70% propellant with pressures between 25 and 55 psig at 70F	Surface aerosols
usually operate between 35 and 55 psig at 70F and may contain only 6 to 10% propellant	Foam aerosols