| Alpha 1 TISSUES | 1 Most vascular smooth muscle
2 Pupillary dilator muscle
3 Pilomotor smooth muscle
4 Prostate
5 Heart
6 Blood Vessels
7 Eyes
8 Urinary Bladder |
| ALPHA 1 Tissue ACTIONS:
1 Most vascular smooth muscle
2 Pupillary dilator muscle
3 Prostate | 1 Contraction (vasoconstriction)
2 Contraction (dilates pupil)
3 Contraction (urinary retention) |
| ALPHA 1 Tissue ACTIONS:
1 Pilomotor smooth muscle
2 Heart
3 Blood Vessels
4 Eyes
5 Urinary Bladder | 1 Erects hair (piloerection)
2 Increase force of contraction
3 Vasoconstriction (increased BP)
4 Mydriasis
5 Increased closure of internal sphincter |
| Alpha 2 TISSUES | 1 Platelets
2 Adrenergic & Cholinergic nerve terminals
3 Some vascular smooth muscle
4 Fat cells |
| ALPHA 2 Tissue ACTIONS:
1 Platelets
2 Adrenergic & Cholinergic nerve terminals
3 Some vascular smooth muscle
4 Fat cells | 1 Aggregation
2 Inhibition of transmitter release
3 Contraction
4 INHIBITION of lipolysis |
| BETA 1 TISSUES | 1 Heart
2 Juxtaglomerular Cells |
| BETA 2 TISSUES | 1 Respiratory smooth muscle
2 Uterine smooth muscle
3 Vascular smooth muscle
4 Skeletal Muscle
5 Human Liver |
| BETA 1 Tissue ACTIONS:
1 Heart
2 Juxtaglomerular Cells | 1 INCREASE force and rate of contraction
2 INCREASE RENIN release |
| Beta 2 Tissue ACTIONS:
1 Respiratory smooth muscle
2 Uterine smooth muscle
3 Vascular smooth muscle | Promotes smooth
muscle relaxation |
| Beta 2 Tissue ACTIONS:
1 Skeletal Muscle
2 Human Liver | 1 Promotes potassium uptake
2 Activates GLYCOGENOLYSIS |
| 1 Positive chonotropic effect
2 Positive dromotropic effect
3 Positive inotropic effect | 1 increased heart rate
2 increased conduction velocity in the AV node
3 increased force of contraction |
| Beta 3 TISSUE AND ACTION | Fat cells;
Activates lipolysis |
| D1 TISSUE AND ACTION | Smooth muscle;
DILATE renal blood vessels |
| D2 TISSUE AND ACTION | Nerve endings;
MODULATES transmitter release |
