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level: Level 3

Questions and Answers List

Question	Answer
DOPAMINE RECEPTOR AGONISTS drugs LONGER duration of action than LEVODOPA LESS RISK of DYSKINESIA, MOTOR FLUCTUATIONS INEFFECTIVE for patients who have NOT responded to LEVODOPA	1 Bromocriptine 2 Ropinirole 3 Pramipexole 4 Rotigotine 5 Apomorphine
ERGOT DERIVATIVE. Similar action with LEVODOPA but hallucinations, confusion, delirium, nausea, and orthostatic hypotension are MORE COMMON DYSKINESIA is LESS PROMINENT May potentially cause PULMONARY & RETROPERITONEAL FIBROSIS May cause mental condition to WORSEN in Psychiatric Illness Used in CAUTION with MYOCARDIAL INFARCTION	Bromocriptine
for Parkinson's Disease 1 ORALLY ACTIVE AGENTS 2 INJECTABLE AND TRANSDERMAL	1 Pramipexole & Ropinirole 2 Apomorphine & Rotigotine
for Parkinson's Disease used for Acute Management of HYPOMOBILITY “off” phenomenon in ADVANCED Parkinson's disease	Apomorphine
administered as a ONCE DAILY transdermal patch that provides even drug levels over 24 hours	Rotigotine
INHIBITS the RENAL TUBULAR SECRETION of Organic Bases Significantly INCREASES the HALF LIFE of Pramipexole	Cimetidine
Used to treat INFLUENZA Has ANTIPARKINSONIAN ACTION LESS EFFICACIOUS than LEVODOPA High Doses: restlessness, agitation, confusion, hallucination May induce ACUTE TOXIC PSYCHOSIS	Amantadine