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level: Level 1

Questions and Answers List

level questions: Level 1

Question	Answer
the use of traditional compounding techniques to manipulate chemical ingredients to produce appropriate dosage forms when no commercial medicine form is available	Extemporaneous compounding
Quality control FOR 1 Oral and topical liquids 2 Hard gelatin capsules	. 1 pH, sp. Gravity, assays, rheological properties, physical observation, physical stability 2 weight variation, dissolution and disintegration
Quality control FOR 1 Ointments, creams and Gels 2 Suppositories, Trouches	. 1 pH, sp. Gravity, assay, rheological properties 2 melting points, dissolution test, physical stability
Quality control FOR 1 Parenteral Preparation	. 1 pH, sp. Gravity, osmolality, color, clarity, particulate matter, sterility
Provide knowledge and skills in good extemporaneous practice, assessment of risk and medication error potential, formulation, quality assurance Demonstrate competency in the necessary extemporaneous preparation skills and pharmaceutical calculations and dilutions	Training and Experience
Clean, Neat, well-lit and quiet working area If aseptic compounding is considered , a clean air environment is needed Measures must be taken to avoid cross contamination Environmental conditions such as temperature, humidity and lighting to limit degradation of product	Environment
Should be developed or obtained Methods used, ingredients added and order of steps is documented.	Formulas
Proper dispensing container for the medications Pharmaceutical-grade chemical is necessary Pharmacist use different chemicals from reliable sources	Chemical and Supplies
It gives processing, packaging and release instructions. For products regularly prepared, master documents should be prepared and checked It should be clear and detailed Worksheets: name and formula of the product, source of formula, unique ID number, manufacturer, batch number of each starting material, date of preparation	Documentation
Risks associated with extemporaneous compounding:	1 Formulation Failure 2 Microbial contamination 3 Calculation errors 4 Starting materials 5 Patient Accessibility issues 6 Health and Safety Risk 7 Therapeutic risks and clinical consequences
1 is easier to learn and use and is more accurate than other types of balances. 2 should be used when picking up weights so that moisture and oils are not transferred to the weights 3 are used in compounding tasks such as preparing ointments and creams or loosening material from the surfaces of a mortar and pestle.	1 Balances 2 Forceps 3 Forceps
1 This is an ideal surface for mixing compounds because of its nonabsorbent surface. 2 The coarser the surface, the finer the triturating, or grinding, that can be done. 3 used for measuring liquids with a volume less than 1.5 mL	1 Compounding Slab 2 Mortar and Pestle 3 Graduates and Pipettes
Prepared by the pharmacist, this sheet indicates the amount of each ingredient needed, lists the procedures to follow, and provides the labeling instructions.	Master Formula Sheet
is one of the most essential parts of the compounding process.	Weighing of the product
A way to combine drugs using a mortar and pestle.	Geometric Dilution Method