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PHARMACOLOGY 2
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wk12-13 Antimicrobials,antifungals.pptx
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Level 2
level: Level 2
Questions and Answers List
level questions: Level 2
Question
Answer
CLASSES OF ANTIBACTERIAL AGENTS (By Mechanism)
1 Cell Wall Inhibitors 2 Cell Membrane Inhibitors 3 Protein synthesis inhibitors 4 Inhibition of nucleic acid synthesis 5 Antimycobacterial agents
1 the POLYSACCHARIDE BACKBONE present in bacterial cell wall that is different from that of all other organisms. The MOST IMPORTANT PROCESS FOR AVOIDING BACTERIAL GROWTH IS TO STOP CELL WALL SYNTHESIS BY INHIBITING THIS 2 What class of antibiotics inhibit this?
1 Peptidoglycan 2 Cell Wall Inhibitors
1 covers the cytoplasm, serve as a SELECTIVE BARRIER and CONTROLS THE INTERNAL COMPOSITION OF THE CELL. Whenever disturbed, macromolecules and ions will outflow, resulting in cell destruction or death. Additionally, changes like discharge of the molecules from interior of the cell, inhibition of respiration, and increased water uptake lead to the cell death. 2 What class inhibits this?
1 Cytoplasmic membrane 2 Cell Membrane Inhibitors
is one of the most important functions in the bacterial cell and humans as well. To cure infectious disease caused by pathogenic bacteria, it is the most important target for the drugs called __, w/c act to disturb any stage of this such as INITIATION & ELONGATION stages.
Protein synthesis inhibitors
One of the most important targets for antibiotic to cure infectious diseases is nucleic acid synthesis The antibacterials of this class can be subdivided into DNA INHIBITORS and RNA INHIBITORS.
Inhibition of nucleic acid synthesis
Inhibition of nucleic acid synthesis 1 INTERFERE WITH THE BACTERIAL TRANSCRIPTION PROCESS in which messenger RNA TRANSCRIPTS of genetic material are produced for later transformation into proteins. 2 also achieved by initiation, elongation, and termination stages; therefore, antibacterial drugs target any one of these processes to inhibit this.
. 1 RNA inhibitors 2 DNA synthesis
A class of antimicrobial drugs that TARGET MYCOBACTERIUM, a genus of Actinobacteria that includes pathogens known to cause serious and infectious disease. these class of antibiotics specifically target these types of microbes.
Antimycobacterial agents What are these microbes? 1 Mycobacterium
1 GROW IN A MOLD-LIKE MANNER on the surface of liquids when cultured. GENUS of ACTINOBACTERIA that includes pathogens known to cause serious and infectious disease. 2 GIVE TYPES OF THESE
1 Mycobacterium 2) 1 Mycobacterium tuberculosis (tuberculosis), & 2 Mycobacterium leprae (leprosy)