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Index
»
TOXICOLOGY
»
TOXIC RESPONSES OF THE RESPIRATORY SYSTEM
»
Level 4
level: Level 4
Questions and Answers List
level questions: Level 4
Question
Answer
Disease: Acute lung injury, chronic obstructive pulmonary disease Acute Effect: Cough, shortness of breath, extreme oro nasal irritation, pulmonary edema, airway hyperreactivity Chronic Effect: Chronic obstructive pulmonary disease, possibly asthma or lung cancer
Acrolein
Disease: Shaver disease, corundum smelter’s lung, bauxite lung Acute Effect: Alveolar edema Chronic Effect: Interstitial fibrosis, emphysema
Aluminum abrasives
Disease: Aluminosis Acute Effect: Cough, shortness of breath Chronic Effect: Interstitial fibrosis
Aluminum dust
Disease: N/A Acute Effect: Oronasal and bronchial irritation, pulmonary edema Chronic Effect: Acute lung injury, chronic bronchitis
Ammonia
Disease: Acute Effect: Bronchitis Chronic Effect: Laryngitis, bronchitis, and lung cancer
Arsenic
Disease: Asbestosis Acute Effect: n/a Chronic Effect: Fibrosis, pleural calcification, lung cancer, mesothelioma
Asbestos
Disease: Farmer lung, compost lung, malt worker’s lung Acute Effect: Bronchoconstriction, cough, chest tightness Chronic Effect: Extrinsic allergic alveolitis (hypersensitivity pneumonitis)
Aspergillus
Disease: Bird fancier’s lung Acute Effect: Bronchoconstriction, cough, chest tightness Chronic Effect: Extrinsic allergic alveolitis (hypersensitivity pneumonitis)
Avian protein
Disease: Berylliosis Acute Effect: Pulmonary edema, pneumonia Chronic Effect: Interstitial granulomatosis, progressive dyspnea, corpulmonarle, fibrosis, and lung cancer
Beryllium
Disease: n/a Acute Effect: Cough, pneumonia Chronic Effect: Emphysema, corpulmonale
Cadmium
Disease: Hard metal disease Acute Effect: Bronchial epithelial hyper and metaplasia Chronic Effect: Peribronchial and perivascular fibrosis
Carbides of tungsten, titanium, or tantalum
Disease: n/a Acute Effect: Cough,hemoptysis, dyspnea, bronchitis, pneumonia Chronic Effect: n/a
Chlorine
Disease: n/a Acute Effect: Oronasal and bronchial irritation Chronic Effect: Fibrosis, lung cancer
Chromium (VI)
Disease: Coal worker’s pneumoconiosis Acute Effect: n/a Chronic Effect: Fibrosis with emphysema
Coal dust
Disease: Byssinosis Acute Effect: Chest tightness, wheezing, dyspnea Chronic Effect: Restrictive lung disease, chronic bronchitis
Cotton dust
Disease: n/a Acute Effect: Airway irritation, hemorrhagic pulmonary edema Chronic Effect:
Hydrogen fluoride
Disease: Siderotic lung disease, silver finisher’s lung, hematite miner’s lung, welder’s lung Acute Effect: Cough Chronic Effect: Silver finisher’s lung with subpleural and perivascular macrophage aggregates; hematite miner’s lung with diffuse fibrosis-like pneumoconiosis; arc welder’s lung with bronchitis
Iron oxides
Disease: n/a Acute Effect: Airway irritation, cough, dyspnea Chronic Effect: Asthma
Isocyanates
Disease: Kaolinosis Acute Effect: n/a Chronic Effect: Fibrosis
Kaolin
Disease: Manganese pneumonia Acute Effect: Acute pneumonia (often fatal) Chronic Effect: Recurrent pneumonia
Manganese
Disease: n/a Acute Effect: Delayed pulmonary edema, skin allergy Chronic Effect: Acute lung injury, chronic bronchitis, non-small-cell lung cancer, nasal cancer
Nickel
Disease: Silo-filler’s diseases Acute Effect: Immediate or delayed pulmonary edema Chronic Effect: Bronchiolitis obliterans, emphysema in experimental animals
Nitrogen oxides