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level: (random questions 2)

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level questions: (random questions 2)

QuestionAnswer
Initial GI symptoms are followed by SEVERE CARDIOVASCULAR EFFECTS (ventricular tachycardia, fibrillation, hypotension) and CNS EFFECTS (agitation, coma, convulsions)(Fluoroacetic acid and its derivatives) Sodium fluoroacetate and Fluoroacetamide
(significant number of suicide or homicides attempts or even accidental consumption) Excessive consumption can cause BLEEDING or HEMORRHAGE anticoagulant used as rodenticidesWarfarin
Acute exposure: respiratory, GI, neurological symptom: lethargy, ataxia, also manifested by headache, seizures, paresthesia, PERIPHERAL NEUROPATHY= tingling sensation in fingers and feet. FumigantsMethyl bromide
o Control plant and fungal diseases o Can cause dermatitis FumigantSulfur
Manifestation: “Cholinergic syndrome” (DUMBBELLS) INSECTICIDESOrganophosphorus compounds
Organophosphorus Treatments1 Atropine 2 Pralidoxime 3 Diazepam
prevents the action of accumulating acetylcholine on the receptors and usually given intravenously to prevent the signs of excess cholinergic stimulationAtropine
Given as an early organophosphorus exposure, and prevent acetylcholinesterase agingPralidoxime
Use to relieve anxiety in mild cases and reduce muscles fasciculations and control convulsions in the more severe casesDiazepam
Usually occurs 2 or 3 weeks after a single exposure of organophosphorus Manifestations (Distal sensorimotor AXONOPATHY)Organophosphate-induced Delayed Polyneuropathy (OPIDP)
Signs and Symptoms: MIOSIS, URINATION, DIARRHEA, SALIVATION, MUSCLE FASCICULATION, and CNS effectsCarbamates
if there is an exposure of carbamates then followed by the organophosphorus compounds, carbamates can offer protection against __Organophosphate-induced delayed polyneuropathy (OPIDP)
Type of additives of carbamate nontoxic and non mutagenicsMethyl carbamates
Carbamate toxicity treatmentAtropine
o Used as medicine as topical treatment of scabies and head lice o In tropical countries, it is used to soaked bed nets to prevent mosquitoes manifestation is PARESTHESIA (tingling, pricking, chilling, numbing, numbness sensation). INSECTICIDESPyrethroids
Convulsion is the prominent aspectHexachlorocyclohexanes & Cyclodienes
readily absorbed thru the skin, the MANIFESTATION IS SAME WITH THE DDT but the TREMOR IS ABSENT on this poisoningLindane and Cyclodienes ( cyclodienes and derivatives.)