level: DRUGS
Questions and Answers List
level questions: DRUGS
| Question | Answer |
|---|---|
| Stable Angina: Nitrates | eg. Long-acting glycerol trinitrate, isosorbide dinitrate, isosorbide mononitrate M.O.A: - vasodilation: reduce SBP& myocardial wall tension -> reducing oxygen. demand - increase contractility and exercise tolerance - transfer blood from non-ischemic to ischemic site |
| Stable Angina: B blockers MOA | - reduce cardiac rate by suppressing LV contraction & arterial pressure - decrease minute volume of heart + oxygen needs in myocardium NB. Cardioselective b-blockers are recommended for PERMANENT treatment of angina |
| Stable Angina: B-blockers Contraindications | HR < 45bpm BP < 90mmHg PQ > or equal to 0.26s II-III AV block Acute LV dysfunction cardiogenic shock bronchial spasm psoriasis |
| Stable angina: ACEI vascular effects | - anti-proliferative effect - reduce atherosclerosis progression - decrease rate of acute coronary syndromes in patient swith LV dysfunction or HF |