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level: Pharmacology

Questions and Answers List

level questions: Pharmacology

QuestionAnswer
Choose the wrong answer. Antibiotics may have :antiviral activity
Choose from the options below an antibiotic with bactericidal action.Gentamicin
Choose from the options below the antibiotic with bacteriostatic action.Doxycycline
Choose from the quinolones below the one that is used only in veterinary medicine:Enrofloxacine
Choose the wrong answer:Vancomycin is considered “Last resort” drug in veterinary medicine for the treatment of infections with Staphylococcus aureus
Deafness is the main undesirable side effect after prolonged use of:Gentamicin
Choose an antibiotic that can be effective in treating infectious meningitis:Ampicillin
Choose from below the substance that is effective against anaerobic bacteria, but also against some protozoa:Metronidazole
Choose the wrong answer: Chloramphenicol is:forbidden in pets
Which of the antibiotics below has the broadest spectrum of action?Tetracycline
Gram negative bacterias have natural resistance to:No answer is correct
From the examples below choose the correct statement:Florfenicol is antibiotic used only in animals
Choose from the options below an antibiotic that belongs to Category 2 (antibiotics from the „second line”):Clindamycin
Choose from the options below: According to the recommendation of use, Vancomycin belongs to:Third category of antibiotics
„These reserved antimicrobials should be used only when there are no alternative antimicrobials authorized for the respective target species and indication”, is a statement that refers to:all Fluoroquinolones and Cephalosporins from the 3rd and 4th generation
„For antibiotics whenever possible, individual treatment of the affected animal(s) (e.g. injectable treatments) should be preferred to group or mass treatment”is a recommendation made by EMA to reduce the risk of:Resistance to the active substance
When should we not wait for the results of sensitivity tests to administer an antibiotic?Never
Choose from the below options and complete the statement: “.......... should be reserved for the treatment of clinical conditions which have responded poorly, or are expected to respond poorly, to other classes of antimicrobials.”Enrofloxacin
In relation to the current tendency to minimize the risk of of developing and spreading antibiotic resistance, choose from the options below the wrong requirement:Antibiotics will be used prophylactically whenever is considered necessary
Choose the wrong steatment:Metaphylaxis can be applied in all categories of animals
Critically important antibioticscan not be used in food producing animals
Currently in the treatment of bacterial meningitis it is recommended to use cephalosporins from the:3rd generation
Which of the following antibiotics work by inhibiting nucleic acid synthesis?Enrofloxacine
For the treatment of Lyme disease it is recommended to use cephalosporins from the:3rd generation
Inhibition of protein synthesis is not the mechanism of action for:Beta lactam antibiotics
Which of the following antibiotics works by inhibiting cell wall synthesis?Penicilline V
Cephalosporines are bactericidal and they act :by inhibiting the bacteria cell wall synthesis
An antibiotic will have a longer duration of action if:if the percentage of active substance molecules linked to plasma proteins is higher
MIC represents:the minimum plasma concentration of an antibiotic at which the development of a microorganism is inhibited
Which is the most important side effect of antibiotics in the GI tract:suppression of normal flora
Which of the following practices increases the risk of developing antibiotic resistance?underdosing
What kind of resistance is that which is predictable and chromosomally mediated?natural resistance
Extrachromosomal mutations - are very often (90%). This type of mechanism of resistance to antibiotics consists in transmission of plasmids from one bacteria to another by:a+b+c conjugation/ phage transduction/ transformation
Which type of resistance to antibiotics corresponds to the image below?extrachromosomal mutations by conjugation
Which type of resistance to antibiotics corresponds to the image below?extrachromosomal mutations by transformation
Which type of resistance to antibiotics corresponds to the image below?extrachromosomal mutations by phage transduction
In emergencies:we can use a broad-spectrum antibiotic
Choose the exception How can healthcare professionals help prevent the spread of antibiotic resistance?prescribing an antibiotic only when it is likely to benefit the patient
It is contraindicated to associate an immunosuppressive with:antibiotics
Classical NSAID:inhibit Cox 1 and Cox2
Cyclooxygenase 2 could be found in:normal tissues
Ketoprofen works by inhibiting synthesis of:a+b+c PGI2/ PGE2/ PGF2α
Choose the exception: The general features of NSAID PK are:a lower degree of binding to plasma protein
Which of the following effects are not specific for NSAID:antiemetic
One of the most common side effect to NSAIDs is:GI disorders
Administration of an NSAID increases the risk of hypoglycaemia when is associated with:sulfonamides
From the list below choose the best analgesic:metamizole
Agranulocytosis is one of the secondary reactions of:metamizole
The anti-inflammatory that can cause liver necrosis due to prolonged use is:paracetamol
The analgesic of first intention in young animals and in pregnant animals is:paracetamol
Choose the correct and complete answer: Kelaprofen 100 mg/ml is an:anti-inflammatory product among classic NSAIDs
Which of the following active substances should not be used in the treatment of inflammation in cats:aspirin
Which of the following is an anti-inflammatory active substance that can selectively inhibit Cox2?celecoxib
Choose the wrong answer: Glucocorticoids inhibit inflammation, by:increasing the release of histamine
Which of the following substances does not fit with the others in the group of inhibitors of cyclooxygenase-2 ?none
Choose the wrong answer: Trocoxil 95 mg chewable tablets is a medicinal product:that contain celecoxib
Thrombostop is a drug indicated for the treatment and prophylaxis of thromboembolic disease. The association with NSAID is:contraindicated
Choose the wrong answer: Flunixin is:a corticosteroid
In order to reduce the risk of ulcer in dogs in case of long-term administration of antinflamatory drugs, it is preferable to use:none
Glucocorticoids are involved in:all answers are correct
Choose the correct answer: Other effect of glucocorticoids, besides anti-inflammatory, is:all answers are correct
Choose from the options below a short-acting glucocorticoid:hydrocortisone
Choose from the options below a long-acting glucocorticoid:dexamethasone
Choose from below what is the most important side reaction following glucocorticoid administration:a+b+c steroid diabetes / fluid retention/ decreases the ability of the body's defense
Choose from the following examples a glucocorticoid obtained from natural sources:hydrocortisone
In animals with thrombocytopenia it is contraindicated to administer:NSAIDs
Choose the wrong answer: Ketofen 10% solution for injection is a product that contains ketaprofen and it is indicated for:treatment of infectious mastitis of the dry cows
Easotic Ear Drops Suspension for Dogs - Multidose is a veterinary medicinal product that contains the following active substances: hydrocortisone aceponate, miconazole nitrate and gentamicin sulphate. In what kind of condition can the product be ineffective?acute otitis caused by Otodectes cynotis
Betamethasone valerate is a potent synthetic corticosteroid (dexamethasone-analogue) used for topical application. It is indicated for thea treatment of:intertrigo (allergic contact dermatitis)
Mastiplan LC, 300mg/20mg (Cefapirin/Prednisolone), intramammary suspension for lactating cows is a medicinal product used for the treatment of clinical mastitis in lactating dairy cows. Taking into account the indication and the active substances from the product, identify the type of etiological agent that cannot be affected by the product.Fusobacterium necrophorum
A dog infected with Microsporum canis can be treated with:Imaverol 100 mg / ml Concentrate for Cutaneous Emulsion, a product containing enilconazole
Which of the following species has a higher sensitivity to Griseofulvin?cat
Griseofulvine is not effective in the treatment of:infection with Malassezia pachydermatis
The mechanism of action of ketoconazole consists of:inhibition of the synthesis of ergosterol
Amfotericin B acts by:increasing the permeability of fungal cell membrane as a result of the modification of the ergosterol structure
Identify the "intruder" of the group:Terbinafine
To which groups of active substances do Fluconazol, Itraconazol and Clotrimazol belong?Azole
Which one from below is not correct when we speak of an ideal anthelmintic? An antihelmintic should have:a narow/targeted spectrum of activity
The mechanism of action of benzimidazoles consists of:bind to beta-tubulin and so they compromise the cytoskeleton
Choose from the substances below which one is highly effective against immature Fasciola hepatica in the liver parenchyma and against the mature stage in the bile ducts:triclabendazole
Choose from the following substances the one that could be effective against adult flukes, tapeworms and roundws:fenbendazole
Which active substance from the examples below is effective only against roundworms?oxibendazole
If we use Levamisol in a cow, we will not have results if the animal is infected with:Dicrocelium lanceolatum
The mechanism of action of levamisol consists of:inhibition of nematode lymph nodes with paralysis of the musculature
In which species Levamisol is rarely used as antiparasitic active substance but as a immune stimulant:sheep
Which of the following active substances is most commonly found in combination with pyrantel for broadening the range of action in dogs?praziquantel
Choose from the following active substance the one that is effective in the treatment of Fasciolosis in sheep:clorsulon
Amitraz is an active substance that belongs to the group of:formamidines
Choose from the pyrethroids below which one is used in the treatment of varoosis in bees:flumethrin
Which of the following substances is not part of the group of Isoxazolines:Fipronil
Frontline contains fipronil. It is effective against:fleas and ticks
Diflubenzuron is part of the group:benzoylureas
Neonicotinoids are not efficient against:mites
In the veterinary pharmacies there are products for dogs that contain fipronil and methoprene. These products are not efficient against?mites
An endectocide is an active substance efficient against:internal and external parasites
Choose the correct answer: Phenylpyrazolesare inhibitors of GABA
Which bacterial process(es) do quinolones and fluoroquinolones inhibit?DNA synthesis
Natural penicillin that can be administered by oral route is:ampicillin
Rifampicin exhibits the following antibacterial mechanism of action:inhibits bacterial RNA synthesis
Aminoglycosides diffuse well into the following biological liquids, with one exception:cerebrospinal fluid