Cephalosporins:V. gen.:

Ceftaroline, ceftobiprole – anti-MRSA drug ceftriaxon, cefotaxim, ceftazidim, cefepim: CSF require dose modification---> severe renal failure(not ceftriaxone) resistant: enterococci ,Listeria monocytogenes , Legionella pneumophila, Rickettsia, Chlamydia, Mycoplasma anaerobes, MRSA, MRSE