S.aureus:

20-40% mortality bacteremia>10 days afer therapy, recurrence 60days afer therapy always should be treated(even one positice hemo) skin, soft tissue, prosthetic, metastatic infection bone, joint, abdominal pain, costovertebral angle, protreacted fever, sweats physical examination:regurgitant murmurs or heart failure, endocarditis, emboli, fundi, conjunctivae, skin, and digits neurologic evaluation, Pain