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Genetics

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Question:

Talk about the elongation process of translation.

Author: H K



Answer:

Lengthening of polypeptide chain by one amino acid per elongation cycle. role of small subunit is to decode the codons while role of large one is peptide-bond synthesis. Second charged tRNA with specific anticodon will go to A site, once bonded to the codon, large subunit catalyzes peptide bonds between the two amino acids present at A and P site tRNA by hydrolyzing the bond between aa and tRNA 3'OH. The dipeptide is attached to tRNA at A site which moves to the P site and the initial tRNA moves to E site to exit, then ribosome-dipeptide-tRNAs move in a distance of a codon (3 nucleotides) P site=peptide A site = amino acid


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H K
H K