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molecular biology 1

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Question:

What is the TBP factor ?

Author: Noura Al shalan



Answer:

TBP is a component of the positioning factor that is required for each type of RNA polymerase to bind its promoter. it binds to TATA box in the minor groove of DNA، as well as TATA box in the minor groove of DNA. The factor for RNA polymerase II is TFIID, which consists of TBP and ~14 TAFs, with a total mass ~800 kD.


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TBP is a component of the positioning factor that is required for each type of RNA polymerase to bind its promoter. it binds to TATA box in the minor groove of DNA، as well as TATA box in the minor groove of DNA.
The factor for RNA polymerase II is TFIID, which consists of TBP and ~14 TAFs, with a total mass ~800 kD.
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