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Question:
Carbimazole & Propylthiouracil are a class of antithyroid drugs (Thionamides) to treat hyperthyroidism, what is their mode of action?
Author: Jade Ann PatersonAnswer:
Metabolised to its active metabolite thiamazole (methimazole). It interferes with the synthesis of thyroid hormones by inhibiting thyroid peroxidase.
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