How does bacterial resistance develop for each antibiotic?

Beta-lactams: decreased concentration of antibiotic at the target, decreased binding to PBP, hydrolysis by beta-lactamases aminoglycosides: modification of the antibiotic, mutation of the ribosome, decreased uptake of antibiotic in the cell, increased efflux quinolones: chromosomal mutations, increased efflux, membrane permeability mutation antimetabolites: changes to the cell membrane