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From course:

BBS2001 Threats and Defence Mechanisms

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Question:

What is the function of regulatory T cells and how is this done?

Author: Mirte Schattorie



Answer:

To suppress the immune response to not harm commensal bacteria this is done by; - production of cytokines that inhibit activation of lymphocytes - expressing CTLA-4 which block B7 molecules -> APCs cannot costimulate the T cells and T cells will not be activated - binding to T cell growth factor, reducing the availability for the T cells


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