What is the neurohumoral compensation

Myocardial damage leads to reduced CO and BP which activates the sympathetic NS This leads to the activation of the RAAS system , vasoconstriction, increase heart rate and contractility Vasoconstriction increases TPR which increases BP RAAS leads to increase fluid retention which leads to increase in cardiac output However in the long term the wall stress and increase oxygen demand leads to hypertrophy and decreased contractility