Question:
How is DNA organised in bacteria?
Author: Alex RapaiAnswer:
The single circular DNA molecule is organised into a series of supercoiled loops that radiate from the central protein core. The nucleoid includes: DNA gyrase and topoisomerase I that maintain the supercoiled state of the DNA, abundant HUs (heat unstable) for packaging. HUs form tetramers around which the DNA is bound (apprx 60 bps). Archea DO NOT have HUs
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