MCB L13-14: Degradation by autophagy – who decides?

Question

Degradation by autophagy – who decides?

Alex Rapai · Accepted Answer

Receptor like proteins needed for specific cargo loading. p62 also known as Sequestosome 1 ➔ ubiquitinated targets. NDP52 and OPTN are sequestosome 1-like receptors (SLRs) ➔
bacterial pathogens ➔ xenophagy and immune response

MCB L13-14

Degradation by autophagy – who decides?

Receptor like proteins needed for specific cargo loading. p62 also known as Sequestosome 1 ➔ ubiquitinated targets. NDP52 and OPTN are sequestosome 1-like receptors (SLRs) ➔ bacterial pathogens ➔ xenophagy and immune response

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