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From course:

MCB L13-14

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Question:

Drugs that cause microtubule stability.

Author: Alex Rapai



Answer:

Taxol: Blocks mitosis by stabilising microtubules, but does not block other functions of microtubules. Nocodazole: Binds to tubulin dimer and prevents its polymerisation into microtubules. Blocks mitosis by causing disassembly of the mitotic spindle and preventing chromosome segregation. Colchicine: Binds to tubulin dimer and prevents its polymerisation. Colcemid: It's structurally related to Colchicine but its action is reversible.


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