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From course:

Pathogens L11-14

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Question:

Cycle

Author: Alex Rapai



Answer:

Intermediate hosts - ingestion of sporulated oocysts. Sporozoites are released, penetrate the intestinal epithelium, and invade macrophages and other types of cells. The parasite undergoes binary fission to form tachyzoites. The host cell will rupture and release the tachyzoites which will invade new host cells and repeat the replicative cycle. Infected macrophages will disseminate the tachyzoites throughout the host during this acute infection.


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