Question:
Give properties of tetracyclins.
Author: H KAnswer:
Mostly PO or Topical (not injectable), broad spectrum and can cause superinfections. Intracellular (work on protein synthesis), natural type is called tetracyclin, synthetic one is Doxycyclin (for acne given in winter to avoid sunlight), Minocyclin (acne) They inhibit 30S prevent tRNA from binding and may give deposits on bone tissues, causing teeth discolorization for young children so we don't give them, it is also contraindicated for pregnancy and bacteriostatic.
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