Fourth-Generation Cephalosporins: Dosage/Route: Adult: 0.5-2 g IM or IV q12h; must be injected for greatest effectiveness q12h for 7-10 d; reduce dose with renal impairment Pediatric: 50 mg/kg per dose q12h IV or IM for 7-10 d Usual Indications: Treatment of moderate to severe skin, urinary tract and respiratory tract infections