ORG MED LEC: The unusual structural groupings in the tetracyclines produce three acidity constants in aqueous solutions of the acid
salts __

Question

The unusual structural groupings in the tetracyclines produce three acidity constants in aqueous solutions of the acid
salts __

LEIGHTON DWIGHT OBILLOS · Accepted Answer

1 pka 1 - acidic (conjugated trione system) 
2 pka 2 - neutral (extending enone system) 
3 pka 3 - basic (ammonium cation moeity)

The unusual structural groupings in the tetracyclines produce three acidity constants in aqueous solutions of the acid salts __