ORG MED LEC: Erythromycin Modification

1 __ for parenteral dosage forms

2 __ for improved oral absorption

3 Acid salts of the dimethylamino group of desosamine moiety

4 Esters of the 2'- hydroxyl group of the desosamine

Question

Erythromycin Modification

1 __ for parenteral dosage forms

2 __ for improved oral absorption

3 Acid salts of the dimethylamino group of desosamine moiety

4 Esters of the 2'- hydroxyl group of the desosamine

LEIGHTON DWIGHT OBILLOS · Accepted Answer

.

1 increase either its water or lipid solubility

2 increase its acid stability

3 glucoheptonate, lactobionate, stearate

4 ethylsuccinate, propionate, available as the lauryl sulfate, known as estolate

Erythromycin Modification 1 for parenteral dosage forms 2 for improved oral absorption 3 Acid salts of the dimethylamino group of desosamine moiety 4 Esters of the 2'- hydroxyl group of the desosamine