Other drugs used in CHF

1 Diuretic therapy and Na+ restriction play an important role in reducing extracellular fluid volume. Diuretics relieve symptoms of heart failure more rapidly than any other oral agent and along with digoxin are first-line drugs for the treatment of CHF. 2 Alpha-adrenergic blocking agents may be used in CHF to improve cardiac function by inducing vasodilation through both direct and reflex actions.