PHARMACOLOGY 2: Therapeutic use: Prevent clot
formation (combined with aspirin)

Mechanism of action
• Facilitates the actions of antithrombin
• Prevents the conversion of fibrinogen into fibrin
• Prevents the activation of factor XIIIa

Adverse effects
• Back pain
• Nausea
• Headache

Question

Therapeutic use: Prevent clot 
formation (combined with aspirin)

Mechanism of action
• Facilitates the actions of antithrombin
• Prevents the conversion of fibrinogen into fibrin
• Prevents the activation of factor XIIIa

Adverse effects 
• Back pain
• Nausea
• Headache

LEIGHTON DWIGHT OBILLOS · Accepted Answer

Direct Thrombin Inhibitors

• Bivalirudin [Angiomax], 
Lepirudin, Argatroban, Desirudin

PHARMACOLOGY 2

Therapeutic use: Prevent clot formation (combined with aspirin) Mechanism of action • Facilitates the actions of antithrombin • Prevents the conversion of fibrinogen into fibrin • Prevents the activation of factor XIIIa Adverse effects • Back pain • Nausea • Headache

Direct Thrombin Inhibitors • Bivalirudin [Angiomax], Lepirudin, Argatroban, Desirudin

Author