What pituitary tumors causing secondary amenorrhea?

Adenomas if <1cm micro if more macro Prolactin adenoma (irresponsive to TRH) GH adenoma (amenorrhea preceeds acromegaly, dx by IGF-1 level, and HGPO dose of GH) Corticotropic adenoma (hypercortisol, dx of free cortisol in urine , midnight cortisol level, and dexamethasone decceleration level) Thyrotropic adenoma (very rare but large) Gonadotropic adenoma (very rare, very high FSH (not frequently LH))