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BIOPHARMACEUTICS

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Question:

Process when DRUG DIFFUSES RAPIDLY ACROSS THE MEMBRANE with BLOOD FLOW AS THE RATE-LIMITING STEP in the distribution of drug

Author: LEIGHTON DWIGHT OBILLOS



Answer:

Perfusion or Flow-Limited Ex. In CHF, has low cardiac output? impaired blood flow, reduced renal clearance thru decreased filtration pressure & blood flow.


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