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BIOPHARMACEUTICS

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Question:

Factors that alter osmotic pressure balance

Author: LEIGHTON DWIGHT OBILLOS



Answer:

1 CHANGES IN ALBUMIN, or blood loss 2 CHANGES IN ELECTROLYTE LEVELS in renal & hepatic disease These results in net flow of plasma water into the interstitial space (EDEMA) Thus increase extravascular drug distribution in some disease state.


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