BIOPHARMACEUTICS: The Pharmacokinetic IMPORTANCE
OF PROTEIN BINDING

Question

The Pharmacokinetic IMPORTANCE
OF PROTEIN BINDING

LEIGHTON DWIGHT OBILLOS · Accepted Answer

1 Drug-protein binding INFLUENCES THE DISTRIBUTION EQUILIBRIUM OF THE DRUG

2 Plasma proteins EXERT A BUFFER and TRANSPORT FUNCTION in the DISTRIBUTION process

3 Only FREE and UNBOUND DRUG ACTS and can LEAVE the circulatory system and DIFFUSE INTO THE TISSUE

The Pharmacokinetic IMPORTANCE OF PROTEIN BINDING