Question:
How is hemosiderin intracellular accumulation?
Author: H KAnswer:
Hb derived pigment, golden yellow - brown, in tissues with excess iron (ferritin micelles...) identified by Prussian blue histochemical rxn (Perls) usually pathological, but small amounts in bone, spleen, liver may be normal. Excessive accumulation - Hemosiderosis- is seen in hemochromatosis rarely could be exogenous
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