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Pharmacology

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Question:

What is sulfonation?

Author: H K



Answer:

Conjugation with sulfate forming sulfate esters, substrates include phenols, alcohol, amines, hydroxylamines. Catalyzed by sulfotransferases which require PAPs as cofactors. Ex: 4-nitrophenol becoming 4-nitrophenol sulfate, cold be also done on dopa, acetaminophen, estrone, naphtalene...)


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Author

H K
H K