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MANUFACTURE FINALS

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Question:

Wet Granulation GENERAL STEPS:

Author: LEIGHTON DWIGHT OBILLOS



Answer:

1. Milling of raw materials. 2. Weighing of raw materials. 3. Dry mixing of milled raw materials by adding the active ingredient, diluent, and internal disintegrant. 4. Wet mixing: incorporating of binder solution (granulating fluid) 5. Granulation and screening of the damp mass using 6-12 mesh screen. 6. Drying. 7. Dry screening through small mesh screen (no. 14-20). 8. Final mixing: addition of lubricant and external disintegrant; From there, it is now ready for further processing either to be encapsulated or to be compressed into powders. 9. Compression.


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