Question:
What are idiosyncratic drug reactions?
Author: H KAnswer:
Not known, neither dynamics or kinetics, interactions between medication and a unique aspect of physiology. Ex: deficiency in glucose-6-phosphate dehydrogenase affecting drug reactions (pentose phosphate pathway difference producing NADPH) this NADPH is used in oxidation of glutathionone drug. Can cause acute hemolytic anemia known as favism (fawwal, after eating fava beans, ID, drugs in G6PD deficient pt)
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