How is the histology and cytokines in asthma?

Infiltrates of mast cells, eosinophils, T cells and neutrophils. if severe eosinophils we may see eosinophilic infiltrates in alveolar septae and arteries. cytokines seen are chemokines (recruitment by epithelia), LT (bronchoconstrictors and pro inflammatory by mast cells and eosinophils, inhibition of them can improve lungs) Histamines (bronchoconstrictor by mast cells), NO (bronchodilator, useful to monitor asthma and inflammation exhaled level), PG D2 (bronchoconstrictor by mast cells, recruits Th2 cell)