What are inflammatory cells seen in COPD?

Neutrophils (potent chemokines IL8 and LTB4 attract neutrophils, increased in sputum and BAL fluid not airway walls, correlate with COPD severity, secrete proteinases (elastase and proteinase-3-A cause of mucus hypersecretion) Macrophages (activated by cigarette smoking, increased in sputum, BAL and lungs, release pro-inflammatory cytokines and proteinases) T cells (increased in airway walls, shift in balance of CD4/CD8 towards CD8, found in large and small airways and parenchyma and arteries, correlated with airflow obstruction