What are tracheobronchial injuries?

Usually caused by chemicals of smoke, toxic inhalations, liquids, or direct airway fire. Symptoms include persistent cough, wheeze, soot-containing secretions (melanoptysis), increased work of breath, erythema, hyperemia, increased pulmonary shunt from atelectasis. Smoke promotes neuropeptide formation, inducing bronchoconstriction and formation of ROS, to potentiate local cellular damage and loss of hypoxemic pulmonary vasoconstriction. Increased blood flow increases PMNs and increase inflammatory response, we get an exudate in airways and possibly airway collapse