How is management of HFrEF?

To reduce mortality (ACE I, BB, MRA, SGLT2i (most imp)) for all pt To reduce hospitalization (SR w/LBBB: use CRT-P/D) Ischaemic etiology (give ICD), A.fib (anticoagulant, digoxin, PVI) CAD (CABG), iron deficiency (ferric carboxymaltose) If advanced pt (heart transplant, MCS as BTT/BTC, long term MCS. As prophylaxis: exercise rehab and multiprofessional disease management