What are etiologies causing cholangitis?

85% stone in bile duct causing bile stasis, other causes are neoplasms, strictures, parasitic infection, congenital abnormalities of duct. Degree of bacterial entry into hepatic venous blood is indicator of the degree of obstruction and biliary pressure. Bacteria in bile are E.coli, Klebsiella, Pseudomonas, Proteus, Enterococci, anaerobics (15% ONLY) C.perfingens and Bacteroides