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GastroEnterology

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Question:

How is liver transplant in case of PBC?

Author: H K



Answer:

Best therapy for end-stage disease, used w/development of major complications of portal HTN, but have poor QoL due to disabling fatigue, intractable pruritis and severe muscle wasting. We may have persistent increase in serum Bi w/out hepatic malignancy, 1-year survival >90%, 5-year survival >80%, AMA may persist after transplant.


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Author

H K
H K