What are clinical findings of hypothyroidism?

Variable depending on (age of onset, duration and severity of deficiency) fatigue, cold intolerance, weight gain, constipation, myalgia and menstrual irregularities are prevalent among people w/normal thyroid function. S&S if gradual are less prominent and more tolerated than if acute (thyroidectomy) We have two changes induced by lack of thyroid hormone (slowing of metabolizing process causes fatigue slow movement weight gain, constipation, bradycardia, delayed relaxation of deep tendon reflexes. And accumulation of matrix GAGs leads to coarse hair and skin, puffy face, enlarged tongue, hoarseness: more in young pt)