Question:
What is subclinical hypothyroidism?
Author: H KAnswer:
Elevated TSH w/normal fT4, most often caused by autimmune (hashimoto) thyroiditis, anti-TPO pt w/ subclinical are at high risk to get overt. May be associated w/increased risk of HF, CAD, coginitive impairment, non-specific symptoms of fatigue, mood alteration (middle aged pt). Tx (can be observed w/out tx, or tx indicated if TSH>10 or TSH between 5-10 w/goiter or + anti-TPO, young pt
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